Status:
COMPLETED
Stepped Care AiTBS 2 Depression Study (Ghent)
Lead Sponsor:
University Hospital, Ghent
Conditions:
Depressive Disorder, Major
Treatment Resistant Depression
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Antidepressant-free unipolar melancholic depressed patients (at least stage 2 treatment-resistant) will be selected by a certified psychiatrist, who will administer (semi-)structured clinical intervie...
Eligibility Criteria
Inclusion
- Antidepressant-free unipolar major depression with melancholic features
- Not responding to at least two trials with an antidepressant
- Aged between 18-65 years old
Exclusion
- Depression with bipolar/psychotic features
- Dysthymia
- Severe personality disorders
- Active substance abuse/dependence within a year prior to inclusion
- Pregnancy or without effective anticonception for the duration of the trial
- ECT non-responder
- No response to more than 9 antidepressants
- Any neurological condition
- Any implanted electronic device susceptible for magnetic field radiation (e.g. pacemaker)
- Any implanted metal device in the head region
- Current or past history of epilepsy
- Neurosurgical interventions
- Known allergic reaction to radiotracers or associated compounds
- Healthy volunteers may be accepted as control subjects.
Key Trial Info
Start Date :
October 5 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2023
Estimated Enrollment :
68 Patients enrolled
Trial Details
Trial ID
NCT03288675
Start Date
October 5 2017
End Date
December 31 2023
Last Update
September 19 2024
Active Locations (1)
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1
University Hospital Ghent
Ghent, East-Flanders, Belgium, 9000