Status:

COMPLETED

Follow-up Study After ACLSCT for Restoration of Corneal Epithelium in Patients With LSCD Due to Ocular Burns

Lead Sponsor:

Holostem s.r.l.

Collaborating Sponsors:

Cromsource

Conditions:

Limbal Stem Cell Deficiency Due to Ocular Burn

Eligibility:

All Genders

Brief Summary

This is a multinational, multicentre, prospective, non-pharmacological follow-up study of the clinical trial HOLOCORE. All patients transplanted with Holoclar in the HOLOCORE clinical trial who consen...

Detailed Description

HOLOCORE FOLLOW-UP prospective study offers the opportunity to collect long-term efficacy and safety data after one or two treatments with Holoclar. Moreover, since Holoclar (study drug used in the ma...

Eligibility Criteria

Inclusion

  • All patients (adults and pediatrics) who completed the HOLOCORE core study and who consent to roll over to the present extension study at the end of the HOLOCORE follow-up.

Exclusion

  • No specific exclusion criterion is considered for this study, except for patients dropping out from the HOLOCORE study or withdrawing consent.

Key Trial Info

Start Date :

December 13 2017

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 31 2023

Estimated Enrollment :

47 Patients enrolled

Trial Details

Trial ID

NCT03288844

Start Date

December 13 2017

End Date

March 31 2023

Last Update

May 26 2023

Active Locations (1)

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1

Hospital San Raffaele

Milan, Italy, 20100