Status:
COMPLETED
Bone Marrow Aspirate Compared to Platelet Rich Plasma for Treating Knee Osteoarthritis
Lead Sponsor:
Andrews Research & Education Foundation
Collaborating Sponsors:
EmCyte Corporation
BioSciences Research Associates, Inc
Conditions:
Knee Osteoarthritis
Eligibility:
All Genders
18-80 years
Phase:
PHASE4
Brief Summary
This study is intended to compare whether bone marrow aspirate concentrate or platelet rich plasma injections is more effective in treating knee osteoarthritis.
Detailed Description
While PRP shows promise in helping restore function to these patients, there are still concerns with PRP's long term outcomes. Another option that has become more popular for physicians treating this ...
Eligibility Criteria
Inclusion
- Male or female age 18-80 years
- Knee osteoarthritis
- Subjects must present with pain or swelling to target knee for at least 4 months
- Kellgren-Lawrence score between 1 and 3 upon x-ray evaluation
- Must be willing and able to provide informed consent
- Willing and able to return for scheduled follow-up visits
Exclusion
- Major mechanical axis deviation of more than 50% into either compartment (varus or valgus )
- Have had a corticosteroid injection within 3 months or a hyaluronic acid injection within 6 months
- History of the following medical conditions:
- diabetes
- autoimmune disorders
- disorders requiring immunosuppression
- rheumatoid arthritis
- hemophilic arthropathy
- infectious arthritis
- Charcot's knee
- Paget's disease of the femur or tibia
- Cancer
- Ongoing infectious disease
- Significant cardiovascular, renal or hepatic disease
Key Trial Info
Start Date :
December 5 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2020
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT03289416
Start Date
December 5 2013
End Date
February 1 2020
Last Update
April 20 2025
Active Locations (1)
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1
Andrews Research & Education Foundation
Gulf Breeze, Florida, United States, 32561