Status:
UNKNOWN
Evaluation of a Strategy Guided by Imaging Versus Systematic Coronary Angiography in Elderly Patients With Ischemia
Lead Sponsor:
University Hospital, Grenoble
Conditions:
Myocardial Infarction
Eligibility:
All Genders
80+ years
Phase:
NA
Brief Summary
The WHO predicts that cardiovascular morbi-mortality will increase by 120-137% within 20 years due to the aging population. Myocardial infarction without ST segment elevation (NSTEMI) is the most comm...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Patients aged 80 years or older
- Hospitalized for NSTEMI with or without ST-segment depression on electrocardiogram (ECG), and with raised blood concentration of troponin T or I. Raised troponin was defined as a value exceeding the 99th percentile of a normal population at the local laboratory at each participating site. A local cardiologist assessed patient eligibility and clinical condition compatible with a doubt for systematic coronary angiography due to a frailty.
- Written informed consent by the patient or the next of kin in case of incapacity.
- Non-inclusion criteria:
- Recurrent or ongoing chest pain refractory to medical treatment
- Haemodynamic instability or cardiogenic shock
- Life-threatening arrhythmias or cardiac arrest
- Contra-indication to CA: Renal failure (creatinine clearance \<15 mL/min by Modification of the Diet in Renal Disease (MDRD)), continuing bleeding problems
- Mechanical complications of MI
- Severe aortic stenosis
- Medical history of severe dementia (documented for more than 3 months)
- Patient under administrative or judicial control
- Patient who are protected under the act
- No health care insurance
Exclusion
Key Trial Info
Start Date :
April 4 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2024
Estimated Enrollment :
1756 Patients enrolled
Trial Details
Trial ID
NCT03289728
Start Date
April 4 2018
End Date
June 1 2024
Last Update
May 30 2023
Active Locations (2)
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1
Clinique Mutualiste
Grenoble, France
2
University Hospital Grenoble
Grenoble, France