Status:
COMPLETED
Microbial and Pharmacological Assessment of Chlorhexidine
Lead Sponsor:
Hôpital Louis Mourier
Conditions:
Oropharynx Abnormality
Pneumonia, Ventilator-Associated
Eligibility:
All Genders
18+ years
Brief Summary
Ventilator-associated pneumonia (VAP) is the most frequent life-threatening nosocomial infection in the ICU. Oropharyngeal colonization with bacterial pathogens is the first step toward lung infection...
Detailed Description
Ventilator associated pneumonia (VAP) is the most frequent life-threatening nosocomial infection in the ICU. Oropharyngeal colonization with bacterial pathogens is the first step toward lung infection...
Eligibility Criteria
Inclusion
- critically-ill patients admitted to the ICU and receiving invasive mechanical ventilation for more than 48 hours
- Non-inclusion criteria:
- cervical or mouth surgery in the last 15 days;
- history of oropharyngeal neoplasm or of cervical or oropharyngeal radiotherapy,
- tracheotomy,
- age under 18
Exclusion
- Patients whose samples retrieved less than 10 to the 3 colony forming unit (CFU)/mL bacteria and those who had two or more missing microbiological samples were secondarily excluded
Key Trial Info
Start Date :
January 27 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2016
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03290105
Start Date
January 27 2014
End Date
June 1 2016
Last Update
September 25 2017
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