Status:

COMPLETED

Combined Use of Contact Aspiration and the Stent Retriever Technique Versus Stent Retriever Alone for Recanalisation in Acute Cerebral Infarction

Lead Sponsor:

Hopital Foch

Conditions:

Acute Ischemic Stroke

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Mechanical thrombectomy (MT) with a stent retriever (SR) device is now the standard intervention in ischemic stroke with large vessel occlusion. Favorable outcome is strongly associated with the succe...

Eligibility Criteria

Inclusion

  • Age 18 and older (i.e., candidates must have had their 18th birthday)
  • Groin puncture carried out within 8 hours of first symptoms
  • Neuroimaging demonstrates large vessel proximal occlusion (distal ICA through MCA bifurcation, M1 or M2)
  • Consenting requirements met according to French laws.
  • With or without intravenous thrombolysis

Exclusion

  • Absence of large vessel occlusion on non-invasive imaging
  • Known or suspected pre-existing (chronic) large vessel occlusion in the symptomatic territory
  • Suspected pregnancy; if, a woman is of childbearing potential, a urine or serum beta human chorionic gonadotropin (betaHCG) test is positive.
  • Severe contrast medium allergy or absolute contraindication to iodinated agents.
  • Patient has severe or fatal comorbidities that will likely prevent improvement or follow-up or that will render the procedure unlikely to benefit the patient.
  • Acute ischemic stroke involving posterior circulation (vertebrobasilar occlusion)
  • Angiographic evidence of carotid dissection or tandem cervical occlusion or stenosis requiring treatment.
  • Patients benefiting from a legal protection
  • Non-membership of a national insurance scheme
  • Opposition of the patient or (in case of inclusion as a matter of urgency) of the trustworthy person

Key Trial Info

Start Date :

October 16 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 28 2020

Estimated Enrollment :

408 Patients enrolled

Trial Details

Trial ID

NCT03290885

Start Date

October 16 2017

End Date

February 28 2020

Last Update

May 26 2020

Active Locations (11)

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Page 1 of 3 (11 locations)

1

CHU Bordeaux

Bordeaux, France

2

CHU Limoges

Limoges, France

3

CHU Montpellier

Montpellier, France

4

CHU Nancy

Nancy, France