Status:

COMPLETED

Venous to Arterial Carbon Dioxide Difference (P₍ᵥ-ₐ₎CO₂): Predictor of Septic Patient Prognosis Depending on the ScvO₂

Lead Sponsor:

Assistance Publique Hopitaux De Marseille

Conditions:

Septic Shock

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

the investigators will include 120 patients with a diagnosis of septic shock in accordance with the definition given by the 2001 expert consensus. Two groups of patients are likely to participate in t...

Eligibility Criteria

Inclusion

  • Patient with a diagnosis of septic shock
  • Initial lactate in patients should be≥ 2 mmol / L.
  • The presence of circulatory insufficiency defined by a systolic blood pressure ≤ 90 mmHg (or a drop in blood pressure≥ 50 mmHg in hypertensive patients)
  • One or more of the following: oliguria defined as diuresis≤ 0,5 mL/ kg / h for at least two hours; the presence of signs of cerebral hypoperfusion; the highlighting of mottling
  • The presence of a femoral arterial catheter and a central venous line in the superior vena cava position
  • Hemodynamic monitoring with semi-invasive monitoring of cardiac output with thermodilution

Exclusion

  • Patient no longer in the initial phase of septic shock
  • Absence of semi-invasive cardiac monitoring with thermodilution
  • Vulnerable people
  • Absence of informed consent

Key Trial Info

Start Date :

June 1 2016

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2019

Estimated Enrollment :

124 Patients enrolled

Trial Details

Trial ID

NCT03292120

Start Date

June 1 2016

End Date

May 1 2019

Last Update

May 8 2019

Active Locations (1)

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Assisitance Publique Hopitaux de Marseille

Marseille, France, 13354