Status:
COMPLETED
Effects of rTMS on Brain Activation in Aphasia
Lead Sponsor:
VA Office of Research and Development
Conditions:
Aphasia, Acquired
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study will investigate the use of repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation method, to improve word-finding abilities in Veterans and non-Veterans with...
Detailed Description
Aphasia, an acquired communication disorder, is a common consequence of left-hemisphere stroke. Persisting, or chronic, aphasia negatively impacts not only interpersonal communication but participatio...
Eligibility Criteria
Inclusion
- Aphasia due to unilateral left-hemisphere stroke
- Greater than 6 months post aphasia onset
- English as a first language
- No contraindications to MRI or TMS including:
- pregnancy
- presence of ferromagnetic substances in the head with the exception of dental fillings, stents or aneurysm clips documented to be MRI compatible
- presence of any implanted devices including cardiac pacemaker, implanted cardiac defibrillator, insulin pump, cochlear implant, or drug infusion device
- history of epilepsy; use of medications that are known to lower seizure threshold
- severe claustrophobia
Exclusion
- History for progressive neurological disease or premorbid language disorder
- Presence of severe motor speech disorder
- Drug or alcohol dependence, or significant mood or behavioral disorder that is not currently stable or medically managed
Key Trial Info
Start Date :
January 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2019
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT03292471
Start Date
January 1 2018
End Date
December 31 2019
Last Update
December 20 2022
Active Locations (1)
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1
VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA
Pittsburgh, Pennsylvania, United States, 15240