Status:
COMPLETED
A Comparison of Methods of Discontinuing Nasal CPAP in Premature Infants <30 Weeks Gestation
Lead Sponsor:
The University of Texas Health Science Center, Houston
Conditions:
Apnea of Prematurity
Respiratory Distress Syndrome
Eligibility:
All Genders
Phase:
NA
Brief Summary
The purpose of this study is to determine if among infants \<30 weeks gestational age on nasal continuous positive airway pressure (NCPAP), whether discontinuing CPAP after gradual reduction in contin...
Eligibility Criteria
Inclusion
- All infants \< 30 weeks by dates, on NCPAP therapy, on caffeine 10mg/kg daily
- Meet CPAP stability criteria for ≥ 12hours (CPAP 6 cm water (H2O), FiO2 \</=0.25 and stable (to maintain sats 85-95%), Respiratory rate consistently less than 60, Mild to no subcostal/intercostal retractions, No Apnea or bradycardia event that requires bag mask ventilation, Less than 3 apnea/brady/desat episodes in any 1 hour period for previous 6 hours, Tolerated time off CPAP during routine CPAP care (\~15 min)
Exclusion
- Major congenital anomalies including congenital heart disease
- Anomalies that prevent discontinuation of NCPAP
- Undergoing current evaluation for and/or treatment of sepsis
Key Trial Info
Start Date :
September 19 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 31 2019
Estimated Enrollment :
66 Patients enrolled
Trial Details
Trial ID
NCT03292562
Start Date
September 19 2017
End Date
March 31 2019
Last Update
March 17 2020
Active Locations (1)
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1
The University of Texas Health Science Center at Houston
Houston, Texas, United States, 77030