Status:
COMPLETED
Association Between Genetic Algorithm to Predict Hypertension Therapy and Response to Treatment
Lead Sponsor:
Geneticure, LLC
Collaborating Sponsors:
Fairview Health Services
Conditions:
Hypertension
Eligibility:
All Genders
30-80 years
Brief Summary
To assess the effectiveness of the use of a patient's genes to predict which hypertension therapy is successful
Detailed Description
Hypertension is known to have a strong heritable component. Previous work has demonstrated that sons of hypertensive patients are more likely to be hypertensive when compared to sons of normotensive i...
Eligibility Criteria
Inclusion
- Subject is able and willing to provide informed consent
- Subject is ≥ 20 and ≤ 85 years of age
- Subject with diagnosis of Hypertension for a minimum of 1 year
- Subject has been on the same class/classes of blood pressure medication for a minimum of 6 months. Note: A change in dosage, frequency, or specific medication is acceptable as long as there have been no changes to the class/classes of medications prescribed.
- Subject with a Body Mass Index (BMI) ≥ 19 and ≤ 45
- Subject is currently prescribed and taking one of the following classes of medications alone or in combination with each other.
- Diuretics (thiazide or thiazide-like)
- ACE Inhibitors
- Angiotensin Receptor Blocker (ARB)
- Beta-blockers
- Ca+ Channel Blockers
Exclusion
- Subject has a diagnosis of secondary hypertension or is experiencing a complication of pregnancy.
- Subject is currently prescribed and taking any additional class of medication(s) for high blood pressure not included in the list above
- Subject has Systolic BP \> 190 or Diastolic BP \> 120 documented within the six months prior to visit.
- Any other reason that the subject is inappropriate for study enrollment in the opinion of the Investigator.
Key Trial Info
Start Date :
March 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 15 2019
Estimated Enrollment :
758 Patients enrolled
Trial Details
Trial ID
NCT03292900
Start Date
March 1 2018
End Date
January 15 2019
Last Update
February 15 2019
Active Locations (1)
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1
Fairview Clinic - New Brighton
New Brighton, Minnesota, United States, 55112