Status:
COMPLETED
An Intervention on Healthy Adults of Probiotics on Gut Flora Metabolisms of Choline
Lead Sponsor:
Huilian Zhu
Conditions:
Healthy
Eligibility:
MALE
18-30 years
Phase:
NA
Brief Summary
The aim of the study is to examine the effects of probiotics intervention on choline metabolites and intestinal microbiota composition using a randomized double blind clinical trial. Also, we proposed...
Detailed Description
Dietary choline (mainly refer to phosphatidylcholine, PC) produce trimethylamine (TMA) through the action of gut flora in vivo. TMA then readily absorbed into systemic circulation and oxidized by hepa...
Eligibility Criteria
Inclusion
- Healthy males at 18 to 30 years old;
- Free from antibiotics and probiotic products for at least 1 month;
- Willing to participate in the study, consume the test product and perform all measurements.
Exclusion
- Sever physical diseases;
- Intolerance to probiotics or eggs
Key Trial Info
Start Date :
July 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2018
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT03292978
Start Date
July 1 2017
End Date
December 31 2018
Last Update
November 13 2019
Active Locations (1)
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1
SunYat-sen University
Guangzhou, Guangdong, China, 510080