Status:
COMPLETED
Intake of Beta-glucan and Postprandial Regulation of Blood Glucose Metabolism in Healthy Subjects
Lead Sponsor:
Oslo Metropolitan University
Collaborating Sponsors:
Mills DA
Nofima
Conditions:
Post Prandial Blood Glucose
Gut Microbiota
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The overall aim is to investigate the intake of beta-glucan in relation to glucose metabolism and satiety in a postprandial study with healthy subjects. The potential effects will be related to change...
Detailed Description
The intervention study will have a fixed order, cross-over design with three test meals containing low (0.5 g / 100 g of product), medium (3.5 g / 100 g of product) and high (8 g / 100 g product) amou...
Eligibility Criteria
Inclusion
- BMI between 18,5 and 27 kg/m2
- Fasting plasma glucose ≤ 6.1 mmol/l
Exclusion
- Chronic metabolic diseases such as diabetes type 1 and 2, coronary heart disease and cancer the last 6 months.
- Intestinal diseases such as chrons disease, ulcerative colitis and irritable bowel syndrome.
- Food allergy and intolerances towards grain and dairy products.
- Pregnant and lactating
- Smokers
- Fasting blood glucose ≥ 6.1 mmol/L
- CRP \> 10 mg/L, measured at baseline (visit 0)
- BMI \<18,5 and \>27 kg/m2
- Planned weight reduction and or ± 5% weight change over the past three months.
- Use of antibiotics last 3 months before study entry and during the study period
- Use of probiotics the last month before study entry and during the study period
- Blood donor last 2 months before study entry and or during the study period
- Not willing to end the use of dietary supplements four weeks prior to study entry and throughout the study period
- Alcohol consumption \> 40g / day
- Hormone treatments (except contraceptives)
Key Trial Info
Start Date :
October 1 2016
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2017
Estimated Enrollment :
14 Patients enrolled
Trial Details
Trial ID
NCT03293693
Start Date
October 1 2016
End Date
June 1 2017
Last Update
September 26 2017
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Oslo and Akershus university College
Oslo, Norway, 0130