Status:
COMPLETED
HARP-Project 1 Cognitive Training
Lead Sponsor:
University of Rochester
Conditions:
Aging
Social Isolation
Eligibility:
All Genders
60+ years
Phase:
NA
Brief Summary
Emerging evidence from social neuroscience suggests that prefrontal cortex (PFC), insular and anterior cingulate cortex (ACC) regulate social and emotional responses to acute threats to social connect...
Eligibility Criteria
Inclusion
- aged ≥ 60 years, community-dwelling, English-speaking, adequate vision and hearing for testing, capacity to give consent based on clinician assessment;
- Telephone Interview for Cognitive Status (TICS) ≥ 31, Geriatric Depression Scale \< 7 (i.e., free of major depression that can interfere with neural efficiency for social-emotional regulation), EXAMINER composite score (a comprehensive executive function battery test package that is sensitive to frontal regions' neural efficiency change) \< .70 (i.e., reflecting decreased neural efficiency of frontal regions compared to cognitively health older adults in general);
- moderate social relation difficulties: identified by World Health Organization Disability Assessment Scale (WHO-DAS), "Getting Along with Other People" domain, at least "moderate" difficulties endorsed; from HARP Database Project screening)
Exclusion
- a self-report clinical diagnosis of dementia or mild cognitive impairment;
- MRI contraindications (e.g., pacemaker, metallic implant, claustrophobia);
Key Trial Info
Start Date :
October 4 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 14 2018
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03293823
Start Date
October 4 2017
End Date
December 14 2018
Last Update
July 5 2019
Active Locations (4)
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1
The Northfield
Fairport, New York, United States, 14450
2
The Highlands
Pittsford, New York, United States, 14534
3
River Edge Manor
Rochester, New York, United States, 14620
4
St. Johns Meadows
Rochester, New York, United States, 14620