Status:
COMPLETED
Effect of Action-Based Cognitive Remediation in Patients With Bipolar Disorder
Lead Sponsor:
Mental Health Services in the Capital Region, Denmark
Collaborating Sponsors:
Lundbeck Foundation
Conditions:
Bipolar Disorder
Cognitive Impairment
Eligibility:
All Genders
18-55 years
Phase:
NA
Brief Summary
PRETEC-ABC aims to assess the effect of a new form of cognitive remediation, Action-Based Cognitive Remediation (ABCR), in patients with bipolar disorder in remission on cognition, and to assess the n...
Detailed Description
The trial will include outpatients with BD in full or partial remission (a score ≤14 on the Hamilton Depression Rating Scale (HDRS) and Young Mania Rating Scale (YMRS). Recruitment will be carried out...
Eligibility Criteria
Inclusion
- Fluent Danish skills and objective cognitive impairment (a total score below cutoff, or scores below cutoff on a minimum of two out of the five subtests (Verbal Learning Test - Immediate, Working Memory Test, Verbal Fluency Test, Verbal Learning Test - Delayed and Processing Speed Test) on the Screen for Cognitive Impairment in Psychiatry - Danish version (SCIP-D).
- Patients must meet the ICD-10 diagnosis of BD (type I and II) confirmed using the Schedules for Clinical Assessment in Neuropsychiatry (SCAN) interview.
Exclusion
- Daily use of benzodiazepines \> 22.5 mg oxazepam, pregnancy, current drug or substance abuse (three months prior to inclusion), previous serious head trauma, severe physical illness, neurological illness, schizophrenia or schizoaffective disorder, dyslexia, claustrophobia, having a pacemaker or other metal implants inside the body and electroconvulsive therapy in the three months prior to inclusion.
Key Trial Info
Start Date :
January 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 25 2020
Estimated Enrollment :
64 Patients enrolled
Trial Details
Trial ID
NCT03295305
Start Date
January 1 2017
End Date
January 25 2020
Last Update
March 4 2020
Active Locations (1)
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1
Mental Health Services, Capital Region of Denmark, Copenhagen University Hospital, Rigshospitalet
Copenhagen, Denmark, 2100