Status:
COMPLETED
Adding a Short Burst of Corticosteroid to the Conventional Treatment of H1 Antihistamines in Emergency Department.
Lead Sponsor:
Chulalongkorn University
Conditions:
Urticaria
Allergy
Eligibility:
All Genders
18-50 years
Phase:
NA
Brief Summary
A randomized, double-blinded, controlled trial of adding a short burst of corticosteroid to the conventional treatment of H1 antihistamines
Detailed Description
Research Methodology Target Population Patients visit emergency room at King chulalongkorn memorial hospital (KCMH) age between 18-50 years who meet the following criteria of acute urticarial such as...
Eligibility Criteria
Inclusion
- Patients visit emergency room at King chulalongkorn memorial hospital (KCMH) age between 18-50 years who meet the following criteria of acute urticarial such as
- eruption of wheals, central swelling of various sizes, with or without surrounding erythema; with or without angioedema
- pruritus or occasional burning sensation
- skin returning to normal appearance, usually within 1-24 hours
Exclusion
- patients who have urticarial for more than 48 hours
- have severe underlying disease such as heart disease, kidney disease, liver disease
- pregnancy
- history of chlorpheniramine maleate, steroid, antihistamines allergy
- history of antihistamine or steroid uses within 48 hours before ED visit
- diabetes mellitus
- suspected of more severe disease or severe allergic reaction
- patients who don't have pruritus
- patients who have history of chronic urticaria
Key Trial Info
Start Date :
October 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 31 2019
Estimated Enrollment :
75 Patients enrolled
Trial Details
Trial ID
NCT03296358
Start Date
October 1 2017
End Date
October 31 2019
Last Update
February 11 2020
Active Locations (1)
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1
Chulalongkorn Hospital
Pathum Wan, Bangkok, Thailand, 10600