Status:
COMPLETED
Comparison of Pulse Chips and Commercial Snacks on Food Intake, Appetite and Blood Glucose in Healthy Young Adults
Lead Sponsor:
University of Toronto
Conditions:
Obesity
Diabetes
Eligibility:
All Genders
18-45 years
Phase:
NA
Brief Summary
Consumers are often forced to eat fast, convenient foods and snacks ("eat on the go") in order to match the pace of their lifestyles. However, these snack options more often than not offer little heal...
Detailed Description
Hypothesis of the study: Inclusion of pulses as part of a snack will lower appetite and post-prandial glycemia (PPG) in comparison to commercial, commonly consumed non-pulse snacks. Overall Objective...
Eligibility Criteria
Inclusion
- Age: ≥18 and ≤45 years
- BMI: ≥ 18.5 and ≤ 29.9 kg/m2
- Fasting serum glucose: ≤ 5.6 mmol/L
- Willing to maintain habitual diet, physical activity pattern, and body weight throughout the trial.
- Willing to maintain current dietary supplement use throughout the trial. On test days, subject agrees not to take any dietary supplements until dismissal from the Department of Nutritional Sciences. Failure to comply will result in a rescheduled test visit.
- Willing to abstain from alcohol consumption for 24 h prior to all test visits.
- Willing to avoid vigorous physical activity for 24 h prior to all test visits.
- Understanding the study procedures and willing to provide informed consent to participate in the study and authorization to release relevant protected health information to the study investigator.
Exclusion
- Fasting blood glucose \> 5.6 mmol/L
- Smoking
- Thyroid problems
- Previous history of cardiovascular disease, diabetes, liver or kidney disease, inflammatory bowel disease, celiac disease, short bowel syndrome, any malabsorptive syndrome, pancreatitis, gallbladder or biliary disease.
- Presence of gastrointestinal disorder or surgeries within the past year.
- Consuming prescription or non-prescription drug, herbal or nutritional supplements known to affect blood glucose or that could affect the outcome of the study as per investigator's judgement.
- Patients who have undergone bariatric surgery at any point.
- Known to be pregnant or lactating.
- Unwillingness or inability to comply with the experimental procedures
- Known intolerance, sensitivity or allergy to pulses or dairy.
- Extreme dietary habits (ie. Atkins diet, very high protein diets, etc.).
- Uncontrolled hypertension (systolic blood pressure ≥ 140 mm Hg or diastolic blood pressure ≥ 90 mm Hg) as defined by the average blood pressure measured at screening.
- Weight gain or loss of at least 10 lbs in previous three months.
- Excessive alcohol intake (more than 2 drinks per day or more than 9 drinks per week)
- Restrained Eaters
Key Trial Info
Start Date :
July 19 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 31 2024
Estimated Enrollment :
26 Patients enrolled
Trial Details
Trial ID
NCT03297931
Start Date
July 19 2017
End Date
May 31 2024
Last Update
March 28 2025
Active Locations (1)
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1
University of Toronto
Toronto, Ontario, Canada, M5S 3E2