Status:
TERMINATED
Fluorescence Imaging in Head and Neck Cancer
Lead Sponsor:
Washington University School of Medicine
Conditions:
Head and Neck Cancer
Cancer of the Head and Neck
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Fluorescent technology continues to advance in the detection of sentinel lymph nodes (SLNs). Currently, this requires switching from near-infrared light to white light to be able to identify the fluor...
Eligibility Criteria
Inclusion
- Adults aged 18 years or older will be considered eligible.
- Patients with head and neck malignancies, such as melanoma, non-melanoma cutaneous malignancies, or oral cavity squamous cell carcinoma. Patients with central neck pathology including thyroid neoplasms, parathyroid neoplasms, and laryngeal neoplasms undergoing surgical resection.
- Candidates for sentinel lymph node biopsy or central neck surgery
- Newly diagnosed with clinically node negative head and neck cancer being staged with sentinel lymph node biopsy.
- Not pregnant or breast feeding.
- Able to understand and willing to sign an IRB-approved written informed consent document.
- Able to understand written or spoken English.
Exclusion
- History of allergy to iodide drugs or shellfish (iodine allergy)
- Pregnant or breast feeding
- Do not fit age criteria
- Prisoners
- Unable to provide written consent
- Contraindications for surgery
- \*Presence of uncontrolled intercurrent illness including, but not limited to, ongoing or active infection of the head and neck, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements
- Receiving any other investigational agents
Key Trial Info
Start Date :
September 14 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 15 2019
Estimated Enrollment :
28 Patients enrolled
Trial Details
Trial ID
NCT03297957
Start Date
September 14 2017
End Date
April 15 2019
Last Update
January 18 2020
Active Locations (1)
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1
Washington University School of Medicine
St Louis, Missouri, United States, 63110