Status:
COMPLETED
Definitive (Chemo)Radiotherapy for Patients With Esophageal Cancer - 3JECROG R-01
Lead Sponsor:
Chinese Academy of Medical Sciences
Collaborating Sponsors:
Hebei Medical University Fourth Hospital
Fujian Cancer Hospital
Conditions:
Esophagus Cancer
Chemoradiation
Eligibility:
All Genders
18+ years
Brief Summary
The aim of this observational study is to retrospectively collect survival data for 3000 primary esophageal cancer patients from multicenter between January 2000 to present. Based on a Cox model, we w...
Eligibility Criteria
Inclusion
- Histologically confirmed squamous cell carcinoma, adenocarcinoma of the esophageal or esophagogastric junction Unresectable or potentially resectable tumor (cT3-4N0-1M0-M1b, without visceral metastasis, according to AJCC 6th) based on standard primary staging by EUS and CT
- Age\>18 years
- No distant metastasis other than supraclavicular lymph nodes
- No prior history of thoracic radiation
- Patients must have normal organ and marrow function as defined below: Leukocytes: greater than or equal to 3,500 G/L; Platelets: greater than or equal to 100,000/mm3 .Hemoglobin:greater than or equal to 10g/L .Total bilirubin: within normal institutional limits; AST/ALT: less than or equal to 1.5 times the upper limit; Creatinine within normal upper limits
Exclusion
- Patients with other cancer history except cervical carcinoma in situ and non-malignant melanoma skin cancer during 5 years before diagnosis of esophageal cancer
- Pregnant or lactating females
- Contraindication for radiotherapy or chemotherapy
Key Trial Info
Start Date :
June 1 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 28 2018
Estimated Enrollment :
2762 Patients enrolled
Trial Details
Trial ID
NCT03298204
Start Date
June 1 2017
End Date
February 28 2018
Last Update
January 2 2019
Active Locations (1)
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1
Department of Radiation Oncology, Cancer Hospital, National Cancer Center, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC)
Beijing, China, 100021