Status:

COMPLETED

Central Sensitization and Alteration of Circulating Neurosteroid

Lead Sponsor:

Seoul National University Bundang Hospital

Conditions:

Arthroplasty, Replacement, Knee

Pain, Postoperative

Eligibility:

FEMALE

Up to 70 years

Brief Summary

For patients who underwent two-stage replacement of both knee joints (one knee surgery - one week term- the other knee surgery), postoperative pain and analgesic usage with patient-controlled analgesi...

Eligibility Criteria

Inclusion

  • Two-staged bilateral total knee arthroplasty (one knee - one week - the other knee)
  • American Society of Anesthesiologists (ASA) class I, II
  • Postmenopausal women aged under 71

Exclusion

  • Patients who have used analgesics before surgery, such as chronic pain patients
  • ≥ ASA class III, including patients with renal impairment or symptomatic cardiovascular disease
  • Patients who refuse to participate in the study or from whom receive informed consent cannot be received.

Key Trial Info

Start Date :

November 20 2017

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 6 2020

Estimated Enrollment :

69 Patients enrolled

Trial Details

Trial ID

NCT03298711

Start Date

November 20 2017

End Date

May 6 2020

Last Update

October 22 2020

Active Locations (1)

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Seoul National University Bundang Hospital

Seongnam-si, Gyeonggi-do, South Korea, 13620