Status:
UNKNOWN
Mechanical Stimulation of the Ovary for Infertility Treatment in Patients With Very Low Ovarian Reserve
Lead Sponsor:
Sheba Medical Center
Conditions:
Ovarian Stimulation
Eligibility:
FEMALE
21-45 years
Phase:
NA
Brief Summary
Examine the possibility that mechanical stimulation and ovarian fragmentation in women with premature ovarian failure or low ovarian reserve intended for egg donation may cause early follicular recrui...
Detailed Description
The women will undergo a surgical laparoscopy during which one of the two technique will ensue. 1. One of the ovaries will be scratched ( 2 mm depth) with a knife. Simultaneously, a piece of the ovar...
Eligibility Criteria
Inclusion
- Healthy women, aged 21-40. with premature ovarian failure.
- Healthy women, with poor ovarian reserve, aged 38-45, undergoing IVF Low ovarian response: recruitment of up to three eggs in previous treatments.
- After the failure of at least 4 cycles.
- Two functioning ovaries, follicular and hormonal response of both ovaries in prior therapies.
- Women candidates for egg donation, and seeking further treatment before switching to egg donation.
Exclusion
- Women with kidney disease.
- Women with infertility factors other than ovarian failure, such as endometriosis, PCOS, male factor.
- Women with one non-functioning ovary, or that was removed.
- Women with an intrauterine or pelvic pathology.
Key Trial Info
Start Date :
October 20 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2019
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT03298750
Start Date
October 20 2017
End Date
September 1 2019
Last Update
October 10 2017
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