Status:

COMPLETED

A Study of Aerobic Exercise for Adolescents With Subthreshold Mood Syndromes

Lead Sponsor:

Guangzhou Psychiatric Hospital

Conditions:

Depressive Symptoms

Hypomania Nos Single Episode or Unspecified

Eligibility:

All Genders

12-14 years

Phase:

NA

Brief Summary

This study will investigate the effects of aerobic exercise on mental states, cognition, and long-term outcomes in adolescents with subthreshold depressive and/or hypomanic syndromes and in non-clinic...

Detailed Description

Subthreshold depressive and hypomanic symptoms are common in adolescents, increasing the risk of developping into depression or bipolar disorder. Preliminary evidence shows that aerobic exercise might...

Eligibility Criteria

Inclusion

  • 2 or more DSM-IV defined depressive symptoms, with one as core symptoms ( lost interest or pleasure in activity or depressed mood), lasting for 1 week.
  • 2 or more DSM-IV defined manic symptoms, last for 4 days, but falling short of the criteria for hypomania; or meeting DSM-5 defined symptoms criteria for hypomania, lasting 2-3 days.
  • non-clinical subjects

Exclusion

  • DSM-IV defined major depressive disorder
  • DSM-IV defined hypo/mania
  • History of or current other Axis I Disorders
  • Diagnosed neurological or musculoskeletal disorder/injury,
  • Uncontrolled cardiovascular or metabolic diseases that are not suitable for running
  • Diagnosed hypertension
  • Other diagnosed serious medical conditions that are not suitable for cycling
  • Severe suicidal ideation
  • Mental retardation
  • Currently participating in a exercise program or activity, defined as 30 minutes of vigorous physical activity 4-5 times per week

Key Trial Info

Start Date :

October 10 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 12 2018

Estimated Enrollment :

224 Patients enrolled

Trial Details

Trial ID

NCT03300778

Start Date

October 10 2017

End Date

January 12 2018

Last Update

August 23 2018

Active Locations (1)

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Guangzhou Brain Hospital

Guangzhou, Guangdong, China, 510370