Status:
TERMINATED
PSMA PET and MRI in Gynecological Cancers
Lead Sponsor:
University of Wisconsin, Madison
Conditions:
Gynecologic Cancer
Eligibility:
FEMALE
18-99 years
Phase:
PHASE2
Brief Summary
The goal of this research is to determine the accuracy of PSMA positron emission tomography (PET) and multi-parametric magnetic resonance (MR) imaging to detect the presence of gynecological cancer ce...
Detailed Description
The investigators will evaluate a novel second-generation low-molecular-weight prostate specific membrane antigen (PSMA)-based positron emission tomography (PET) agent, 18F-DCFPyL, to determine the pr...
Eligibility Criteria
Inclusion
- Inclusion Criteria for healthy female controls N=12 (includes up to 6 Dosimetry participants):
- Women with no suspected gynecological cancer.
- No contraindications for MR or PET imaging.
- Greater than or equal to 18 years of age.
- Scheduled to undergo a hysterectomy and/or salpingo-oophorectomy
- Inclusion Criteria for female controls (Dosimetry):
- Women with or without suspected gynecological cancer.
- No contraindications for MR or PET imaging.
- Greater than or equal to 18 years of age.
- Inclusion Criteria for gynecological cancer patients (N=40):
- Women with known or suspected gynecological cancer
- No contraindications for MR or PET imaging.
- Greater than or equal to 18 years
- Have had or are scheduled to undergo a hysterectomy and/or salpingo-oophorectomy
- Exclusion Criteria:
- Women that are pregnant or breast-feeding.
- Age \<18
- Inability to provide informed consent on their own behalf
- Severe kidney dysfunction (GFR \<30 mL/min/1.73m2)
Exclusion
Key Trial Info
Start Date :
November 15 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 20 2020
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT03302156
Start Date
November 15 2017
End Date
January 20 2020
Last Update
September 5 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Wisconsin, Madison
Madison, Wisconsin, United States, 53705