Status:
COMPLETED
The Use of Chewing Gum for Xerostomia and Hyposalivation After Radiotherapy for Oral and Oropharyngeal Tumors
Lead Sponsor:
Odense University Hospital
Collaborating Sponsors:
Danish Cancer Society
Odense Patient Data Explorative Network
Conditions:
Head and Neck Cancer
Radiation Therapy Complication
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study evaluates the possible benefits of a tasteless and sugar free chewing gum as a salivary stimulant for head and neck cancer patients treated with curative intended radiotherapy.
Detailed Description
Radiation-induced xerostomia and hyposalivation are frequent side effects after completed treatment for oral and oropharyngeal cancers. This may induce eating and swallowing difficulties, compromised ...
Eligibility Criteria
Inclusion
- Over 18 years of age
- Diagnosed with oral or oropharyngeal carcinoma
- Received curative intended radiation therapy (primary or postoperative), 60-66Gy including concurrent chemotherapy
- Within 6 to 60 months after radiation therapy
- Complains of xerostomia level 1 (according to Danish Head and Neck Cancer group)
- Written informed consent
Exclusion
- Poor teeth condition or full set of dentures
- Recurrence of cancer or palliative treatment
Key Trial Info
Start Date :
September 1 2016
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2019
Estimated Enrollment :
109 Patients enrolled
Trial Details
Trial ID
NCT03302676
Start Date
September 1 2016
End Date
January 1 2019
Last Update
March 14 2019
Active Locations (1)
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1
Odense University Hospital
Odense, Danmark, Denmark, 5000