Status:

COMPLETED

Combined Peripheral (BreEStim) and Central Electrical Stimulation (tDCS) for Neuropathic Pain Management - Spinal Cord Injury

Lead Sponsor:

The University of Texas Health Science Center, Houston

Conditions:

Pain Management

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

This study looks at the effect of combined breathing-controlled electrical stimulation (BreEStim) and transcranial direct current stimulation (tDCS) on neuropathic pain after spinal cord injury, amput...

Eligibility Criteria

Inclusion

  • between 18 and 75 years
  • male and female subjects
  • has neuropathic pain after traumatic spinal cord injury
  • has chronic pain, \>3 months
  • is stable on oral pain medications at least two weeks. (patients are allowed to continue their pain medications, i.e., no change in pain medications.)

Exclusion

  • currently adjusting oral pain medications for their neuropathic pain
  • have pain, but not neuropathic (e.g., from inflammation at the incision wound of the residual limb or neuroma)
  • have a pacemaker, or other metal and/or implanted devices
  • have amputation in their arm(s)
  • have spinal cord injury (SCI) involving impairment of arms
  • have cognitive impairment from brain injury or are not able to follow commands, or to give consent
  • have asthma or other pulmonary disease
  • are not medically stable
  • have preexisting psychiatric disorders
  • alcohol or drug abuse
  • have a history of seizures/Epilepsy, or taking benzodiazepines, anticonvulsants, and antidepressants.
  • Mini-mental state examination (MMSE), a brief 30-point questionnaire test that is commonly used in the literature, will be used to screen for cognitive impairment. A brain injury patient with a score of 24 or lower on MMSE will be excluded.

Key Trial Info

Start Date :

April 1 2015

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2017

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT03302793

Start Date

April 1 2015

End Date

December 1 2017

Last Update

January 24 2019

Active Locations (1)

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TIRR

Houston, Texas, United States, 77030