Status:
UNKNOWN
Microembolisation After Carotid Revascularisation
Lead Sponsor:
University Hospital, Geneva
Conditions:
Carotid Stenosis
Eligibility:
All Genders
18-100 years
Brief Summary
Microembolisation identified on diffusion-weighted magnetic resonance imaging (DW-MRI) is recognized as an important outcome measure for carotid revascularization procedures such as carotid stenting (...
Eligibility Criteria
Inclusion
- Patients presenting a symptomatic (ipsilateral ischemic stroke, TIA located in the carotid artery territory or retinal ischemia) carotid stenosis between 50% and 99% (according to NASCET and ECST criteria)
- Patients presenting an asymptomatic carotid stenosis between 60% and 99% (according to NASCET and ECST criteria) Patients who accept the informed consent
Exclusion
- Important neurological deficit with NIHSS \>7 (or severe aphasia) at time of inclusion
- Previous known cognitive impairment
- Pregnancy
- Presence of contraindication based on ground of multidisciplinary team decision:
- For surgery:
- High bifurcation Intracranial extension of the carotid stenosis Patients with tandem lesions High suspicion of severe siphon stenosis Patients with previous irradiation of the cervical region Patients with restenosis after endarterectomy
- For stenting; Excessive arch vessel or carotid artery tortuosity and in particular presence tortuosity ≤90 degrees in the cervical segment Excessive aortic arch plaque burden Patients older than 70 years Unfavourable anatomic disposition as described above Co-morbidities that may preclude the use of a periprocedural dual antiplatelet regime.
- For CT-scan Iodine allergy Renal insufficiency
- For MRI Pacemaker Any other metallic implants Claustrophobia
- For ultrasound Bad quality ultrasound (patient morphology or equipments
Key Trial Info
Start Date :
March 30 2017
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 30 2019
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT03303430
Start Date
March 30 2017
End Date
March 30 2019
Last Update
October 6 2017
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Fisch Loraine
Geneva, Switzerland, 1205