Status:
RECRUITING
Concordance of Imaging and Pathology Diagnosis of Extranodal Tumour Deposits
Lead Sponsor:
Imperial College London
Collaborating Sponsors:
Pelican Cancer Foundation
Conditions:
Adenocarcinoma of the Rectum
Eligibility:
All Genders
16+ years
Phase:
NA
Brief Summary
Any patient with a suspected primary adenocarcinoma of the colon, sigmoid or rectum undergoing surgery are eligible. The date of surgery must be known prior to registration. This trial aims to determi...
Detailed Description
A prospective interventional multi-centre study, COMET aims to prove the accuracy of imaging diagnosis of extranodal tumour deposits (TD) and their adverse effect on prognosis of colorectal cancers. T...
Eligibility Criteria
Inclusion
- Suspected primary adenocarcinoma of the colon, sigmoid or rectum (proven by biopsy taken as part of routine clinical practice, patients to be withdrawn if not subsequently adenocarcinoma on pathology).
- Amenable to surgical resection.
- Disease spread assessed on imaging
- Patients having primary surgery and those undergoing neoadjuvant treatment will be included.
- All must have had baseline staging scans and those undergoing neoadjuvant therapy must also have had a post-treatment scan.
- Patients aged 16 years and over
Exclusion
- Patients with recurrent tumours
- Synchronous tumours
- Under the age of 16 years
- Unable to give informed consent.
Key Trial Info
Start Date :
October 16 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2031
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT03303547
Start Date
October 16 2017
End Date
December 1 2031
Last Update
October 17 2024
Active Locations (1)
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1
Royal Marsden Hospital NHS Foundation Trust
London, Surrey, United Kingdom, SM2 5PT