Status:

UNKNOWN

A Comparison of Exparel to Bupivacaine in TAP Block for Abdominal Gynecologic Surgery

Lead Sponsor:

Abington Memorial Hospital

Conditions:

Gynecologic Cancer

Post Operative Pain

Eligibility:

FEMALE

18-99 years

Phase:

PHASE3

Brief Summary

This study evaluates the comparison between liposomal bupivacaine versus bupivacaine HCl in Transversus Abdominis Plane blocks for gynecologic surgery on the length of stay in the hospital, total narc...

Detailed Description

The proposed pilot study is evaluating the use of Exparel ™ in an anesthesia protocol for patients undergoing major lower abdominal gynecologic surgery. Exparel ™ is a formulation of liposomal bupivic...

Eligibility Criteria

Inclusion

  • all patients undergoing planned exploratory laparotomy
  • TAP blocks placed after the laparotomy incision is closed, but before the patient is awake, and placed under ultrasound guidance with correct identification of the correct abdominal plane.
  • Consent for TAP block signed by patients preoperatively by anesthesiology

Exclusion

  • All pregnant patients
  • All patients under 18 years of age
  • minimally invasive surgery such as laparoscopy or robotic assisted laparoscopy
  • medical contraindications to use of bupivacaine or liposomal bupivacaine such as severe hepatic and/or renal disease

Key Trial Info

Start Date :

August 1 2016

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2017

Estimated Enrollment :

128 Patients enrolled

Trial Details

Trial ID

NCT03304444

Start Date

August 1 2016

End Date

October 1 2017

Last Update

October 9 2017

Active Locations (1)

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Abington Hospital Jefferson Health

Abington, Pennsylvania, United States, 19001