Status:

RECRUITING

Prognostic Factors in Zygapophyseal Osteoarthritis Infiltration: a Prospective Cohort Study

Lead Sponsor:

Hospital Israelita Albert Einstein

Conditions:

Degenerative Arthropathy of Lumbar Spinal Facet Joint

Eligibility:

All Genders

18+ years

Brief Summary

Magnet Resonance Image findings of facet osteoarthritis and patient characteristics are prognostic factors for improving or worsening the clinical outcome after treatment with facet infiltration.

Detailed Description

1. Introduction: Low back pain is one of the significant health problems; studies have shown that it can affect 80-85% of people throughout life; consisting of the second major cause of work withdrawa...

Eligibility Criteria

Inclusion

  • Inclusion criteria
  • The following are inclusion criteria for participants:
  • Older than 18 years;
  • Fluent or native Portuguese language speaker;
  • Continuous or intermittent low back pain for at least three months;
  • Low back pain with or without irradiation to the gluteal region indicating facet syndrome (pain is aggravated by spine extension or bending toward the affected side; pain is exacerbated by prolonged sitting or walking up steps, as well as retaining one position for a prolonged time);
  • Failure of traditional treatment includes, but is not limited to, physical or drug therapy;
  • Understand the purpose of the study;
  • Voluntarily provide a free and informed consent form, by themselves or through their partners, and complete the questionnaires, before undergoing infiltration, over the telephone or online during the follow-up.
  • Exclusion criteria
  • The following are exclusion criteria for participants:
  • Younger than 18 years old,
  • Symptomatic lumbar spinal stenosis with claudication or radiculopathy;
  • Evidence of radiculopathy;
  • Active rheumatologic diseases;
  • Congenital or acquired deformities of the lumbar spine;
  • Fracture or sequel of lumbar spine fracture of traumatic, pathological or osteoporotic origin;
  • Surgical manipulation of the lumbar spine;
  • MRI scans of limited quality and incomplete sequences;
  • Treated with systemic steroids less than one month before the IFI;
  • Treated with IFI with steroids within the last six months;
  • Diagnosed with uncontrolled diabetes mellitus;
  • History of allergy to anesthetics or adverse reaction to steroids;
  • Pregnant women or women who breastfed;
  • Who could not be contacted over the phone during follow-up.

Exclusion

    Key Trial Info

    Start Date :

    September 1 2017

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    December 1 2027

    Estimated Enrollment :

    147 Patients enrolled

    Trial Details

    Trial ID

    NCT03304730

    Start Date

    September 1 2017

    End Date

    December 1 2027

    Last Update

    October 17 2024

    Active Locations (1)

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    Hospital Israelista Albert Einstein

    São Paulo, São Paulo, Brazil, 05652-900