Status:
UNKNOWN
The Effect of Remote Ischemic Preconditioning in Aortic Valve Replacement Surgery
Lead Sponsor:
Laval University
Collaborating Sponsors:
Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Conditions:
Aortic Valve Stenosis
Cardiopulmonary Bypass
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The study objective is to verify if a non-invasive remote ischemic preconditioning procedure (blood pressure cuff on the arm) is cardioprotective when applied before an aortic valve replacement surger...
Eligibility Criteria
Inclusion
- Planned isolated aortic valve replacement (stenosis based)
- Age ≥ 18 years
Exclusion
- Pregnancy
- Left ventricular dysfunction (LVEF\< 50%)
- Myocardial Infarct (\< 7days)
- Coronary artery disease (documented with \>50% stenosis)
- Coronary artery bypass grafting
- Chronic renal insufficiency (creatinine \>175 mmol/L or dialysis)
- Endocarditis
- Sternotomy redo
- Deep vein thrombosis to the compressed limb
- Emergency procedure
- TAVI procedure
- Planned off pump coronary artery bypass
- MAZE procedure
Key Trial Info
Start Date :
April 11 2014
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2024
Estimated Enrollment :
140 Patients enrolled
Trial Details
Trial ID
NCT03305094
Start Date
April 11 2014
End Date
December 1 2024
Last Update
March 10 2023
Active Locations (1)
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1
Hôpital Laval
Québec, Quebec, Canada, G1V 4G5