Status:
UNKNOWN
Atrial Electromechanical Function in Endurance Athletes With and Without Atrial Fibrillation
Lead Sponsor:
University of Toronto
Collaborating Sponsors:
Unity Health Toronto
Conditions:
Paroxysmal Atrial Fibrillation
Eligibility:
MALE
45-65 years
Brief Summary
This study evaluates cardiac structure and function differences between healthy endurance trained athletes with atrial fibrillation and healthy age matched endurance trained athletes without atrial fi...
Detailed Description
Regular physical activity, including vigorous exercise, lowers cardiovascular risk factors, including the risk of developing Atrial Fibrillation (AF), one of the most commonly diagnosed types of arrhy...
Eligibility Criteria
Inclusion
- ALL participants:
- endurance athlete (cyclist, runner, triathlete or other) who participate in vigorous year-round training of 4-6 hours per week for a minimum of 20 years
- participation in atleast one major competition per year (marathon/triathlon/endurance competition)
- sinus rhythm during all assessments
- Inclusion criteria specific to endurance athletes with AF:
- diagnosed with lone paroxysmal AF in the last 4 years
- able to verify diagnosis (ECG or Holter verification/proof of diagnosis),
- can be on any type of medication.
- Inclusion criteria specific to healthy endurance athletes without AF:
- previous participation in Athlete's Heart Study
- has completed resting cardiac magnetic resonance imaging and resting electrocardiogram
Exclusion
- females
- no more than \>1 hour per week of resistance training
- treatment or prior diagnosis of cardiovascular disease, valvular disease, hypertension, heart failure, diabetes, thyroid disorder, sleep apnea, current/recent viral disease, chronic inflammatory disease
- previous (within 10 years) or current smoking
- recreational drug use or alcohol consumption in excess of accepted standards
- inability to provide informed consent
- inability to verify AF diagnosis (if AF athlete).
Key Trial Info
Start Date :
January 30 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 1 2021
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT03305744
Start Date
January 30 2018
End Date
August 1 2021
Last Update
November 3 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Goldring Center for High Performance
Toronto, Ontario, Canada, M5S 2C9