Status:

COMPLETED

Effects of Left Ventricular Assist Device Implantation on the Phenotype of Blood Platelets and Leucocytes

Lead Sponsor:

University Hospital, Toulouse

Conditions:

Cardiac Insufficiency

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

To compare in vivo platelet and leukocyte activation and phenotype before and after Left ventricular assist device (LAVD) implantation

Detailed Description

The present study plan to investigate platelet activation in vivo using a variety of biomarkers previously identified as sensitive to high shear stress in patients with severe aortic valve stenosis be...

Eligibility Criteria

Inclusion

  • elective implantation of LAVD (Heartmate II),
  • written informed consent to the study
  • Patients with health insurance

Exclusion

  • treatment or procedure that could affect platelet functions or turn-over(low-dose aspirin is allowed).
  • Pregnancy or breastfeeding
  • Juridical Protection

Key Trial Info

Start Date :

October 3 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 23 2019

Estimated Enrollment :

4 Patients enrolled

Trial Details

Trial ID

NCT03306017

Start Date

October 3 2017

End Date

January 23 2019

Last Update

August 20 2019

Active Locations (1)

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1

University Hospital

Toulouse, France