Status:
COMPLETED
Impact of Brain Connectome and Personality on Cognitive Rehabilitation in Multiple Sclerosis
Lead Sponsor:
State University of New York at Buffalo
Conditions:
Multiple Sclerosis
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
This study aims to apply baseline MRI and neuropsychological measures to predict patient responses to behavioral cognitive rehabilitation. Training will take place over 12 weeks, 1 hour per day, 5 day...
Detailed Description
The participant will be asked to make a total of two (2) visits, approximately 90 days apart. Each visit will involve: neuro-performance testing, and self-report questionnaires. Each study visit is ex...
Eligibility Criteria
Inclusion
- For all subjects:
- males and females above age 18
- fluent in English
- education \>9 years
- Additional inclusion criteria for MS patients are as follows:
- Clinically definite MS diagnosis
- Expanded Disability Status Scale (EDSS) ≤ 6.5
- MS patients must be relapse-free and stable from the time of their MRI acquired for the CEG-MS study
- Willing and able to comply with the study procedures for the duration of the trial
Exclusion
- history of serious medical or psychiatric illness (other than MS in the patient group) that may affect cognitive functioning
- color-blindness
- history of developmental disability
- past or current alcohol or substance dependence
- History of major depressive disorder, bipolar disorder, or psychotic disorder predating the onset of MS
- History of traumatic brain injury as defined by trauma causing loss of consciousness or transient post-traumatic or retrograde amnesia exceeding 5 min
- Other pathology related to MRI abnormalities
Key Trial Info
Start Date :
November 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 20 2018
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT03306875
Start Date
November 1 2017
End Date
October 20 2018
Last Update
November 26 2018
Active Locations (1)
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1
Jacobs Comprehensive Multiple Sclerosis Treatment and Research Center
Buffalo, New York, United States, 14203