Status:

COMPLETED

Fractional CO2 Laser Therapy for Survivors of Breast Malignancies

Lead Sponsor:

Ohio State University Comprehensive Cancer Center

Conditions:

Breast Carcinoma

Cancer Survivor

Eligibility:

FEMALE

Phase:

NA

Brief Summary

This pilot clinical trial studies how well fraction carbon dioxide (CO2) laser therapy works in treating vaginal atrophy in patients with breast cancer. Fraction CO2 laser therapy uses intense beams o...

Detailed Description

PRIMARY OBJECTIVES: I. To demonstrate the feasibility of fractionated CO2 laser treatments in patients with breast cancer with vaginal atrophy by determining treatment completion rates and tolerabili...

Eligibility Criteria

Inclusion

  • Women with non-metastatic breast cancer with any hormone receptor and Her 2 neu status who have completed surgery, chemotherapy, and radiation and are currently on endocrine therapy, single agent Herceptin, or observation
  • Symptoms of urogenital atrophy including dyspareunia or vaginal dryness

Exclusion

  • Patients with metastatic breast cancer
  • Vaginal stenosis which would not allow vaginal probe to be placed (based on physician exam)
  • Active genital infection at the time of enrollment (if present initially, can be treated and then patient can be re-evaluated for eligibility)
  • Pelvic organ prolapse greater than stage II
  • Prior reconstructive pelvic surgery involving mesh
  • Hormone replacement therapy, vaginal estrogen therapy, DHEA, or biosynthetics within 6 weeks prior to enrollment

Key Trial Info

Start Date :

November 16 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 5 2022

Estimated Enrollment :

66 Patients enrolled

Trial Details

Trial ID

NCT03307044

Start Date

November 16 2017

End Date

May 5 2022

Last Update

March 20 2023

Active Locations (1)

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1

Ohio State University Comprehensive Cancer Center

Columbus, Ohio, United States, 43210