Status:

UNKNOWN

uPAR-PET/MRI in Patients With Prostate Cancer for Evaluation of Tumor Aggressiveness

Lead Sponsor:

Rigshospitalet, Denmark

Conditions:

Prostate Cancer

Eligibility:

MALE

18+ years

Phase:

PHASE2

Brief Summary

Prospective study to evaluate the value of uPAR-targeted PET/MR scan using the tracer 68Ga-NOTA-AE105 in patients with newly diagnosed prostate cancer

Detailed Description

Prostate cancer is one of the most frequent types of cancer in men. The characteristics of the disease varies significantly among patients where some have an indolent type of cancer, from which they w...

Eligibility Criteria

Inclusion

  • Histologically verified prostate cancer
  • Capable of understanding written information and giving informed consent
  • Planned to enter active surveillance strategy or undergo therapy with curative intent (surgery or radiotherapy)

Exclusion

  • Obesity (Body weight over 140 kg)
  • Known allergy to 68-Ga-NOTA-AE105
  • Metallic components in the body that contradicts MRI scan
  • Severe claustrophobia making the person unable to complete an MRI scan

Key Trial Info

Start Date :

November 21 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2022

Estimated Enrollment :

52 Patients enrolled

Trial Details

Trial ID

NCT03307460

Start Date

November 21 2017

End Date

April 1 2022

Last Update

November 23 2020

Active Locations (1)

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1

Rigshospitalet

Copenhagen, Denmark, 2100