Status:

ACTIVE_NOT_RECRUITING

Extended Follow-up of Women Who Received One, Two, and Three Doses of the HPV Vaccine in the Costa Rica Vaccine Trial (CVT), ESCUDDO-CVT Study

Lead Sponsor:

National Cancer Institute (NCI)

Conditions:

Human Papillomavirus Infection

Human Papillomavirus-Related Malignant Neoplasm

Eligibility:

FEMALE

Brief Summary

This study is extending follow up of women who participated in the Costa Rica Vaccine Trial (CVT) and received one dose or two doses of the human papillomavirus (HPV) vaccine, along with a group of wo...

Detailed Description

PRIMARY OBJECTIVES: I. Estimate the change in antibody levels between years 11 and 20. II. Estimate the proportion of individuals who become seronegative (i.e.: serorevert) between years 11 and 20. ...

Eligibility Criteria

Inclusion

  • Participation in the CVT Long Term Follow-Up (LTFU) study

Exclusion

  • A random subset of the three-dose women

Key Trial Info

Start Date :

July 2 2018

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

February 28 2026

Estimated Enrollment :

991 Patients enrolled

Trial Details

Trial ID

NCT03309033

Start Date

July 2 2018

End Date

February 28 2026

Last Update

July 23 2025

Active Locations (1)

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Agencia Costarricense de Investigaciones Biomédicas (ACIB)

Liberia, Guanacaste Province, Costa Rica, 50101