Status:
COMPLETED
Lung and Gut Microbiome in Chronic Obstructive Pulmonary Disease
Lead Sponsor:
Peking University Third Hospital
Conditions:
Chronic Obstructive Pulmonary Disease
Eligibility:
MALE
40-80 years
Brief Summary
Increasing evidence have implied that microbiota from airway and gut might be involved in the pathogenesis of chronic obstructive pulmonary disease (COPD). However, the cross-talk between respiratory ...
Detailed Description
Despite the high prevalence of chronic obstructive pulmonary disease (COPD), there continues to be a large gap in our understanding of disease pathogenesis and mechanisms accounting for large variabil...
Eligibility Criteria
Inclusion
- males aged 40-80;
- diagnosed with COPD according to the GOLD guidelines;
- clinically stable patients without medication changes or exacerbation in two months;
- smoking history of more than 10 pack years
Exclusion
- diagnosed with unstable cardiovascular diseases, significant renal or hepatic dysfunction or mental incompetence;
- diagnosed with asthma, active pulmonary tuberculosis, diffuse panbronchiolitis, cystic fibrosis, clinically significant bronchiectasis, exacerbation of COPD or pneumonia in two months;
- prescribed immunosuppressive medications.
Key Trial Info
Start Date :
June 15 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 15 2016
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT03310164
Start Date
June 15 2014
End Date
February 15 2016
Last Update
October 16 2017
Active Locations (1)
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1
Peking University Third Hospital
Beijing, Beijing Municipality, China, 100191