Status:

COMPLETED

Registry of Preterm Newborns With Severe Pulmonary Hypertension

Lead Sponsor:

University of Colorado, Denver

Collaborating Sponsors:

Mallinckrodt

Conditions:

Pulmonary Hypertension

Preterm Infant

Eligibility:

All Genders

Up to 45 years

Brief Summary

The purpose of this prospective research registry is to collect data on treatment strategies and outcomes for premature newborns with severe pulmonary hypertension (PH).

Detailed Description

There is a lack of consensus on the role of inhaled nitric oxide (iNO) therapy and other pulmonary vasodilators for the treatment of severe pulmonary hypertension (PH) in premature newborns (\<34 week...

Eligibility Criteria

Inclusion

  • Premature newborns 23-34 weeks gestation
  • Echocardiographic evidence showing systemic or suprasystemic levels of PH, or \> 5% difference in pre-post ductal saturation if echo is not available.
  • Fraction of inspired oxygen (FiO2) \>0.60 in the first 72 hours after birth

Exclusion

  • None

Key Trial Info

Start Date :

August 1 2017

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 2 2022

Estimated Enrollment :

232 Patients enrolled

Trial Details

Trial ID

NCT03310346

Start Date

August 1 2017

End Date

July 2 2022

Last Update

March 6 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University of Colorado

Aurora, Colorado, United States, 80045