Status:
COMPLETED
Negative-Positive Valence Domains in Anxiety and Depression
Lead Sponsor:
University of California, San Diego
Collaborating Sponsors:
University of California, Los Angeles
Conditions:
Anxiety
Depression
Eligibility:
All Genders
18-55 years
Brief Summary
Anxiety and depression are highly prevalent and disabling conditions that frequently co-occur, and are costly to the individual and society. Despite important advances in our understanding of these di...
Detailed Description
Participants presenting to the UCSD and UCLA primary care clinics will be screened as part of their routine visit using the Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder 7 (GAD...
Eligibility Criteria
Inclusion
- Positive for anxiety and/or depressive symptoms.
- Score on the PHQ-9 and OASIS.
- Between the ages of 18-55, inclusive.
- Have signed informed consent document(s) indicating that participant understands the purpose of and procedures required for the study and willing to participate in the study.
- Have sufficient proficiency in English language to understand and complete interviews, questionnaires, and all other study procedures.
- Have telephone or easy access to telephone.
- History of brain injury with evidence of neurological deficits, neurological disorders, or severe or unstable medical conditions that might be compromised by participation in the study (to be determined by primary care provider).
- Current and regular use of a medication that could affect brain functioning.
- Must not have MRI contraindications such as: cardiac pacemaker, metal fragments in eyes/skin/body (shrapnel), aortic/aneurysm clips, prosthesis, by-pass surgery/coronary artery clips, hearing aid, heart valve replacement, shunt (ventricular or spinal), electrodes, metal plates/pins/screws/wires, or neuro/bio-stimulators (TENS unit), persons who have ever been a metal worker/welder, history of eye surgery/eyes washed out because of metal, inability to lie still on one's back for 60 minutes; prior neurosurgery; tattoos with metal dyes, unwillingness to remove body piercings, and pregnancy.
- Intact or correctable vision and hearing.
Exclusion
Key Trial Info
Start Date :
September 1 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 30 2017
Estimated Enrollment :
248 Patients enrolled
Trial Details
Trial ID
NCT03310398
Start Date
September 1 2013
End Date
June 30 2017
Last Update
October 16 2017
Active Locations (1)
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1
UCSD Psychiatry Clinical Research
La Jolla, California, United States, 92093-0855