Status:

UNKNOWN

Conduct of Nasal High Flow Oxygen in Acute Respiratory Failure

Lead Sponsor:

Hôpital Louis Mourier

Conditions:

Acute Respiratory Failure With Hypoxia

Hypoxemia

Eligibility:

All Genders

18+ years

Brief Summary

Although many studies have investigated the clinical benefits of nasal high flow during acute hypoxemic respiratory failure, there is no data (and even less so recommendations) on how to best conduct ...

Detailed Description

Nasal high flow oxygen therapy is increasingly used as a first-line treatment for hypoxemic acute respiratory failure, because of its remarkable tolerance (in comparison with NIV) and its physiologica...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Patients aged 18 or older
  • admitted to the intensive care unit (ICU) or to the intermediate care for acute hypoxemic respiratory failure (whatever the cause)
  • treated with nasal high flow oxygen therapy
  • with a minimal FiO2 of FiO2≥50% and a gas flow ≥40 L/min
  • anticipated duration of nasal high flow therapy greater or equal to 24 hours
  • Non-inclusion Criteria:
  • prophylactic, post-extubation nasal high flow therapy
  • palliative nasal high flow therapy (do-not-resuscitate order)
  • Exclusion criteria
  • \- nasal high flow therapy administered for less than 24 hours

Exclusion

    Key Trial Info

    Start Date :

    July 9 2018

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    November 1 2018

    Estimated Enrollment :

    100 Patients enrolled

    Trial Details

    Trial ID

    NCT03311087

    Start Date

    July 9 2018

    End Date

    November 1 2018

    Last Update

    July 20 2018

    Active Locations (10)

    Enter a location and click search to find clinical trials sorted by distance.

    Page 1 of 3 (10 locations)

    1

    Service de Réanimation Médico-Chirurgicale

    Colombes, France, 92700

    2

    Service de Réanimation Médicale

    Dijon, France

    3

    Service de Réanimation Médicale

    Grenoble, France

    4

    Service de Réanimation

    Longjumeau, France