Status:
COMPLETED
Periodontal Therapy in Thalassemia Major Patients
Lead Sponsor:
King Saud University
Conditions:
Thalassemia Major
Chronic Periodontitis
Eligibility:
All Genders
10-18 years
Phase:
NA
Brief Summary
The study aims to evaluate the effect of local non surgical periodontal therapy on the systemic pro-inflammatory markers in the β-thalassemia (TM-β) patients with chronic periodontitis and systemicall...
Detailed Description
Treatment modalities in patients with thalassemia include long-term transfusion therapy, iron chelation, splenectomy, allogeneic hematopoietic transplantation and supportive measures. Attempts to down...
Eligibility Criteria
Inclusion
- Written and verbal consent
- (TM-β) patients with gingivitis
- Age: ≥10 years
- Patients who have received or are receiving iron chelation therapy with deferasirox, calcium, vitamin D, and regular erythrocyte transfusion.
Exclusion
- Presence of hepatitis B or C or HIV-AIDS (Human immunodeficiency Virus- Acquired immunodeficiency syndrome).
- Presence of any other known systemic disease.
- Use of antibiotics or anti-inflammatory drugs within the past 6 months.
- Dental prophylaxes in the last 6 months
Key Trial Info
Start Date :
January 11 2016
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 16 2017
Estimated Enrollment :
52 Patients enrolled
Trial Details
Trial ID
NCT03311243
Start Date
January 11 2016
End Date
June 16 2017
Last Update
October 18 2017
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