Status:
COMPLETED
Intracranial Collaterals in Acute Stroke and Clinical Outcome
Lead Sponsor:
Assiut University
Conditions:
Collateral Circulation, Any Site
Eligibility:
All Genders
18-75 years
Brief Summary
Assessment of the evolution of intracranial collaterals and its relationship with functional outcomes in acute ischemic stroke (AIS) patients treated with IV tissue plasminogen activator (tPA).
Detailed Description
Intracranial collaterals Assessment in acute ischemic stroke In clinical practice, infarct growth does not always progress to involve the full extent of the vascular territory, even if the affected in...
Eligibility Criteria
Inclusion
- I
- Patient presenting to the emergency department with symptoms consistent with ischemic stroke.
- Age \> 18 yrs.
- Evidence of a visible and symptomatic intracranial occlusion on baseline CT-angiography (intracranial ICA, M1 MCA segment +/- intracranial ICA, proximal M2 MCA).
- Treatment with IV tPA.
Exclusion
- Intracranial hemorrhage (ICH) identified on baseline CT.
- Previous moderate to large stroke in the ipsilesional hemisphere.
- Modified Rankin Scale \> 2 at baseline.
- Unable to have CT-angio performed due to recent estimated creatinine clearance eCCr\<60 ml/min, contrast allergy or other reasons.
- Any terminal illness (patient not expected to survive \> 1 year).
Key Trial Info
Start Date :
November 23 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 1 2021
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT03311386
Start Date
November 23 2017
End Date
August 1 2021
Last Update
September 16 2021
Active Locations (1)
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1
Assiut university
Asyut, Egypt, 71511