Status:

COMPLETED

Simplification Study of HIV-1 Infected Patients With Virological Suppression Under the Combination of Lamivudine (150 mg BID) Plus Raltegravir (400 mg BID) Switching to Lamivudine (300 mg QD) Plus Raltegravir (1200 mg QD) : Roll-over Study of the RALAM

Lead Sponsor:

Judit Pich

Collaborating Sponsors:

Fundacion Clinic per a la Recerca Biomédica

Conditions:

HIV Infections

HIV-1-infection

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

Phase 3b, single arm, single site simplification study of HIV-1 infected patients with virological suppression under the combination of Lamivudine (150 mg BID) plus Raltegravir (400 mg BID) switching ...

Eligibility Criteria

Inclusion

  • Patients in the switch arm who have completed the 24-week follow-up of RALAM (NCT02284035) study and remain virologically suppressed (viral load \<50 copies/mL) on dual therapy with lamivudine plus Raltegravir
  • Patients who have signed informed consent to participate in the study.

Exclusion

  • Pregnancy, lactation, or planned pregnancy during the study period
  • Any disease or history of disease which, in opinion of the investigator, might confound the results of the study or pose additional risk to patient treatment
  • Hepatitis B co-infection

Key Trial Info

Start Date :

May 2 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 30 2022

Estimated Enrollment :

33 Patients enrolled

Trial Details

Trial ID

NCT03311945

Start Date

May 2 2018

End Date

November 30 2022

Last Update

July 18 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Hospital Clínic i Provincial de Barcelona

Barcelona, Spain, 08036