Status:
COMPLETED
Personal FET in RIF Patients According to Histological Dating of Endometrial of Natural/ Hormone Replacement Cycle
Lead Sponsor:
Reproductive & Genetic Hospital of CITIC-Xiangya
Conditions:
Infertility, Female
Eligibility:
FEMALE
20-40 years
Phase:
NA
Brief Summary
At present, the evaluation criterion of endometrial receptivity is controversial. The development of a molecular diagnostic tool, the endometrial receptivity array (ERA) for diagnosis of endometrial r...
Eligibility Criteria
Inclusion
- The inclusion criteria for RIF group were:
- •unexplained repeated implantation failure (RIF) which is defined as the absence of a gestational sac on ultrasound at 5 or more weeks after embryo transfer (ET) after 3 embryo transfers with high quality embryos or after the transfer of ≥10 embryos in multiple transfers.
- The inclusion criteria for control group were:
- age \<35 years;
- regular menstrual cycles of 24-35 days;
- baseline follicle- stimulating hormone (FSH) \< 9.0 IU/L;
- endometrial thickness ≥8.0 mm on the day of hCG administration.
Exclusion
- uterine abnormalities (double uterus, bicornuate uterus, unicornuate uterus);
- intrauterine adhesions（moderate - severe）, endometriosis, adenomyosis, untreated hydrosalpinx, uterine fibroids (submucosal fibroids, nonmucosal fibroids \>4.0 cm and/or endometrial pressure)
- history of adverse pregnancy (including spontaneous abortion, stillbirth, and fetal malformation).
Key Trial Info
Start Date :
October 17 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 28 2018
Estimated Enrollment :
155 Patients enrolled
Trial Details
Trial ID
NCT03312309
Start Date
October 17 2017
End Date
February 28 2018
Last Update
January 11 2022
Active Locations (1)
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1
Reproductive & Genetic Hospital of CITIC-XIANGYA
Changsha, Hunan, China, 410000