Status:

COMPLETED

Preventing Diabetes With Digital Health and Coaching

Lead Sponsor:

Omada Health, Inc.

Collaborating Sponsors:

University of Nebraska

Wake Forest University Health Sciences

Conditions:

PreDiabetes

Eligibility:

All Genders

19+ years

Phase:

NA

Brief Summary

The goal of this randomized controlled trial is to determine the efficacy of a digital diabetes prevention program for improving weight, glucose control, and secondary risk factors among people with p...

Detailed Description

Prediabetes is an increasingly prevalent condition, characterized by glucose levels that are above normal but below the threshold for diabetes. Previous studies have demonstrated that intensive lifest...

Eligibility Criteria

Inclusion

  • Receives care at University of Nebraska Medical Center or Nebraska Medicine
  • Age 19 years or older
  • HbA1c 5.7%-6.4%
  • Overweight (BMI 25+ or 22+ if Asian)
  • Planning to reside in recruitment area for next 12 months
  • Able to engage in moderate aerobic physical activity
  • Medically stable
  • Able to provide informed consent
  • Willing to accept random assignment to treatment

Exclusion

  • Not meeting all inclusion criteria
  • Diagnosed with Type I or II diabetes
  • Diagnosed with congestive heart failure, coronary artery disease, chronic obstructive pulmonary disease, pulmonary hypertension
  • Diagnosed with dementia or probable Alzheimer's disease
  • Taking oral hypoglycemic agents
  • Participating in a concurrent weight management program or interventional research protocol
  • Unable to engage in physical activity
  • On a prescribed medical diet
  • Had bariatric surgery within the past 3 years or planning surgery within the next 12 months
  • Anti-obesity or diabetes therapy within the preceding 4 months
  • Any mental health condition, including eating disorders or alcohol/substance use, which would preclude full participation
  • Self-report as currently pregnant or within 6 weeks of having given birth (or planning to become pregnant in the next 12 months)
  • Unstable cardiac disease (i.e. heart attack/failure or stroke in the last 6 months, or in cardiac rehabilitation)
  • On dialysis or an active organ transplant list
  • Chronic kidney disease
  • Untreated thyroid disease
  • Cancer within the last 5 years unless skin cancer (i.e. currently or within the last 5 years in chemotherapy or radiation treatment)
  • Unwilling to accept random assignment

Key Trial Info

Start Date :

November 1 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 31 2020

Estimated Enrollment :

598 Patients enrolled

Trial Details

Trial ID

NCT03312764

Start Date

November 1 2017

End Date

August 31 2020

Last Update

February 23 2021

Active Locations (1)

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1

University of Nebraska Medical Center

Omaha, Nebraska, United States, 68198-4365