Status:
UNKNOWN
Comparison of ACAF and ACCF in the Treatment of Cervical OPLL
Lead Sponsor:
Shanghai Changzheng Hospital
Conditions:
Ossification of Posterior Longitudinal Ligament
Eligibility:
All Genders
45-70 years
Phase:
NA
Brief Summary
Background: Dr. Shi recently proposed a new technique as Ossification of anterior decompression surgery, which is also called anterior controllable antedisplacement and fusion (ACAF) , for ossificatio...
Detailed Description
Background: Although anterior and posterior decompression surgery are both reported to treat patients with myelopathy caused by OPLL（Posterior longitudinal ligament ossification）. The surgical strateg...
Eligibility Criteria
Inclusion
- patients aged 45-70 years, without gender limitation, are willing to sign informed consent;
- patients diagnosed with posterior longitudinal ligament ossification of the cervical spine;
- patients with limbs numbness, walking instability, banding and other spinal cord, nerve root compression symptoms, may be associated with urinary dysfunction, conservative treatment is invalid or gradually increased;
Exclusion
- Cervical ligamentous ossification, cervical trauma, cervical cancer, cervical tuberculosis and other inflammatory diseases;
- accompanied by thoracolumbar spine and other spine parts of the disease affect the clinical symptoms of patients;
- associated with amyotrophic lateral sclerosis and other motor neuron diseases and other neurological diseases;
- poor health condition, unable to tolerate surgery;
- patients (or their guardians) can not give full informed consent for adult dysfunction;
- patients who have participated in other clinical trials in the past 1 month
- patients with active hepatitis B (including HBeAg) or serological markers (HBsAg or / and HBeAg or / and HBcAb), hepatitis C, tuberculosis, cytomegalovirus infection, severe fungal infection or HIV infection;
- patients with active peptic ulcers within 3 months before randomization.
- patients with malignant neoplasms
Key Trial Info
Start Date :
May 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2022
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT03312985
Start Date
May 1 2017
End Date
January 1 2022
Last Update
November 17 2017
Active Locations (1)
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1
Shanghai Changzheng Hospital
Shanghai, Shanghai Municipality, China, 200001