Status:

COMPLETED

Trial to Evaluate the Safety and Immunogenicity of a Multivalent Pneumococcal Conjugate Vaccine in Adults 60 Through 64 Years of Age

Lead Sponsor:

Pfizer

Conditions:

Pneumococcal Infections

Eligibility:

All Genders

60-64 years

Phase:

PHASE2

Brief Summary

This is a Phase 2, randomized, double-blinded study with a 2-arm parallel design. Healthy adults aged 60 through 64 years of age with no history of pneumococcal vaccination will be randomized equally ...

Eligibility Criteria

Inclusion

  • Male or female adults \>/= 60 to \</=64 years of age (from the 60th birthday up to, but not including, the 65th birthday) at enrollment.
  • Healthy adults, including adults with preexisting stable disease, defined as disease not requiring significant change in therapy or requiring hospitalization within 3 months before receipt of investigational product, as determined by medical history, physical examination, laboratory screening, and clinical judgment of the investigator.
  • Female subjects who are not of childbearing potential.

Exclusion

  • Previous vaccination with any licensed or investigational pneumococcal vaccine, or planned receipt through study participation.
  • History of microbiologically proven invasive disease caused by S pneumoniae.
  • Serious chronic disorder including metastatic malignancy, severe chronic obstructive pulmonary disease (COPD) requiring supplemental oxygen, end-stage renal disease with or without dialysis, clinically unstable cardiac disease, or any other disorder that, in the investigator's opinion, excludes the subject from participating in the study.

Key Trial Info

Start Date :

October 10 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 10 2018

Estimated Enrollment :

444 Patients enrolled

Trial Details

Trial ID

NCT03313037

Start Date

October 10 2017

End Date

December 10 2018

Last Update

December 26 2019

Active Locations (14)

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Page 1 of 4 (14 locations)

1

Anaheim Clinical Trials, LLC

Anaheim, California, United States, 92801

2

Clinical Research of South Florida

Coral Gables, Florida, United States, 33134

3

Avail Clinical Research, LLC

DeLand, Florida, United States, 32720

4

Qps-Mra, Llc

South Miami, Florida, United States, 33143