Status:
COMPLETED
Effect of Air Cleaner on the Indoor Allergen Sensitized Allergic Rhinitis Patients
Lead Sponsor:
Yonsei University
Conditions:
Allergic Rhinitis
Eligibility:
All Genders
19-65 years
Phase:
NA
Brief Summary
This study aimed to assess the impact of air cleanser on allergic rhinitis patients and indoor air quality. Air cleaners will be installed in the bedrooms and living rooms of the mite allergic rhiniti...
Detailed Description
The most important principle in the treatment of allergic diseases is to avoid or reduce exposure to the causative antigen. Causative agents that induce allergic diseases or exacerbate symptoms are cl...
Eligibility Criteria
Inclusion
- Adults between 19 and 65 years of age
- Allergy specialist diagnosis of Moderate to severe persistent allergic rhinitis
- Retrospective Rhinoconjunctivitis total symptom score higher than 7
- Allergy against house dust mite: Skin prick test, with a more than 3 mm wheal, Serum specific IgE higher than 0.35 kUA/L measured by ImmunoCAP
- Who can read and write Korean
- Participants those who voluntarily agreed to this study
Exclusion
- Allergy against seasonal allergens (tree, grass, weed pollens)
- Patients with rhinitis due to other causes (drug induced rhinitis or infectious rhinitis etc.)
- Patients with severe anatomical abnormality that may cause nasal blockage such as nasal septum deviation or nasal polyps
- Chronic systemic corticosteroids (≥ 3 months continuous use in past 12 months)
- Participants planning to move or change residence within the study period.
- Staying away from the home continuously for more than 5 days in the study period.
- Having air cleaner previously
- Having indoor smoker
- If pregnancy test is positive or pregnancy is possible during study period.
- Any other reason the participants is deemed unsuitable for participation in clinical trials
Key Trial Info
Start Date :
August 16 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 22 2017
Estimated Enrollment :
44 Patients enrolled
Trial Details
Trial ID
NCT03313453
Start Date
August 16 2017
End Date
December 22 2017
Last Update
February 13 2018
Active Locations (1)
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1
Division of Allergy and Immunology Department of Internal Medicine, Yonsei University College of Medicine
Seoul, South Korea, 03722