Status:
COMPLETED
Study to Assess OCT: RNFL and GCL in MS Patients
Lead Sponsor:
Tampa Bay Uveitis Center, LLC
Conditions:
Multiple Sclerosis
Eligibility:
All Genders
18+ years
Brief Summary
The purpose of this study is to collect preliminary data on retinal nerve fiber layer and ganglion cell layer damage in multiple sclerosis (MS) patients, using optical coherence tomography (OCT). For ...
Detailed Description
Hypothesis: Multiple sclerosis results in axonal degeneration which can be assessed objectively and non-invasively by serial OCT measurements of the RNFL and GCL. This will be a prospective cross-sec...
Eligibility Criteria
Inclusion
- Age 18 or older
- Pregnant women will be excluded by self declaration
- Male or female
- A diagnosis of MS, that meets the 2010 Revised McDonald Diagnostic Criteria
- A visual acuity of 20/400 or better in at least one eye
Exclusion
- Any ocular disease than prevents assessment of the optic nerve and macula by OCT
- Advance glaucoma with optic nerve damage
- Any optic neuropathy not diagnosed as ON associated with MS
- A diagnosis of Macular Degeneration
- Any previous ocular trauma
- Any medical history of a cerebrovascular accident
- Any planned ocular or systemic elective surgery during study duration
- Any contraindication to a comprehensive dilated ophthalmic examination
- Inability to give informed consent
Key Trial Info
Start Date :
February 9 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 30 2021
Estimated Enrollment :
73 Patients enrolled
Trial Details
Trial ID
NCT03313843
Start Date
February 9 2018
End Date
April 30 2021
Last Update
June 2 2021
Active Locations (2)
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1
Tampa Bay Uveitis Center
New Port Richey, Florida, United States, 34655
2
Tampa Bay Uveitis Center
Tampa, Florida, United States, 33618