Status:

COMPLETED

Na+ Channel mRNA Regulation in Heart Failure

Lead Sponsor:

University of Minnesota

Conditions:

Heart Failure

Eligibility:

All Genders

Brief Summary

Human heart failure (HF) has been associated with reduced cardiac sodium channel current and other electrical remodeling. Recently, the investigators have shown that downregulation of cardiac Na+ chan...

Detailed Description

Altered gene expression has been traditionally focused on transcriptional regulation. Nevertheless, recent large-scale analyses have revealed that as many as half of all changes in the amounts of mRNA...

Eligibility Criteria

Inclusion

  • ischemic or non-ischemic cardiomyopathy Healthy Donor heart

Exclusion

  • N/A
  • Not diagnosed with ischemic or non-ischemic cardiomyopathy

Key Trial Info

Start Date :

August 1 2011

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 1 2021

Estimated Enrollment :

48 Patients enrolled

Trial Details

Trial ID

NCT03313882

Start Date

August 1 2011

End Date

August 1 2021

Last Update

March 2 2022

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