Status:

COMPLETED

Remediation of Visual Perceptual Impairments in People With Schizophrenia

Lead Sponsor:

University of Rochester

Collaborating Sponsors:

New York University

Weill Medical College of Cornell University

Conditions:

Schizophrenia

Schizoaffective Disorder

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

The purpose of this study is to evaluate the effectiveness of a visual remediation intervention for people with schizophrenia. The intervention targets two visual functions that much research has show...

Detailed Description

It is increasingly clear that people with schizophrenia have a range of visual perception impairments, including in low-level vision (e.g., acuity, contrast sensitivity) and mid-level vision (e.g., pe...

Eligibility Criteria

Inclusion

  • SCID-5 diagnosis of schizophrenia;
  • 18-60 years old;
  • speaks English;
  • able to complete the MATRICS Consensus Cognitive Battery (MCCB) at the baseline assessment (for R33);
  • a raw score of 37 or greater on the Wide Range Achievement Test, Reading subtest (WRAT-3), to establish a minimum reading level (6th grade) and to estimate premorbid IQ; and
  • clinically stable as indicated by no antipsychotic medication changes in the last month or if on depot, no change in the past 2 months.

Exclusion

  • history of intellectual disability, or developmental or neurological disorder;
  • history of brain trauma associated with loss of consciousness for \> 10 minutes or behavioral sequelae;
  • alcohol or substance use disorder within the last 6 months; and
  • history of eye disease (e.g., glaucoma, retinopathy).

Key Trial Info

Start Date :

June 1 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 31 2025

Estimated Enrollment :

79 Patients enrolled

Trial Details

Trial ID

NCT03314129

Start Date

June 1 2018

End Date

May 31 2025

Last Update

September 5 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

University of Rochester Medical Center - Strong Ties Community Support Clinic

Rochester, New York, United States, 14623

2

New York Presbyterian Hospital

White Plains, New York, United States, 10605